Skin swabs could pave the way for non-invasive Covid testing

Surrey's researchers used non-invasive swabs to collect sebum - an oily waxy substance produced by the body's sebaceous glands - from 83 hospitalised patients, some of whom were diagnosed with Covid-19. The team also collected blood and saliva samples for this comparative study. 

Covid-19 has been found to significantly change the makeup of lipids (fats and oils) of biofluids such as blood or sebum.  

By measuring changes in lipids and other metabolites of the samples, the research team observed that (with a 1.0 score being the most accurate and sensitive) blood samples scored 0.97.

Covid tests for the nose and throat may not be needed in the future (PA)

Skin swab tests were not far behind though, scoring 0.88, alongside saliva tests scoring 0.80.

Professor Melanie Bailey, co-author of the study from the University of Surrey, said: "Covid-19 has shown us that rapid testing is vital in monitoring and identifying new illnesses. In our research, we explored the relationships between different biofluids, and what changes in one part of the human body can tell us about the overall health of a patient.

"Our results show that, while blood is the most accurate way of testing for this virus, skin swabs are not too far behind - in fact, the skin swab results were surprisingly accurate." 

Professor Debra Skene, co-author and Section Lead of Chronobiology at the University of Surrey, also added: “The work we demonstrate in this study that profiles metabolites in three different biofluids (serum, saliva and sebum) offers promise in distinguishing people positive for Covid-19 from people negative for Covid-19.

"The promise of a non-invasive test for Covid-19 is a reason for much of society to rejoice.” 

The research was published in Scentific Reports.