A 21-YEAR-OLD woman has gone missing after a night out at a North-East pub.

Police are appealing for information as to the whereabouts of Roxanne Louise Ryan, who is from the Owton Manor area of Hartlepool.

She went to Newcastle on Wednesday and was last seen in The Goose pub in Eldon Square at around 5.15pm.

"Roxanne was last seen wearing a black dress with three gold buttons on the front, black flower patterned leggings with black calf length boots with a white three quarter length wool coat," a spokeswoman for Cleveland Police said. "She was wearing silver hoop earrings and has a ring with a ball on it through her nose on the right hand side.

"She is described as having brown straight shoulder length hair, 5ft 8ins tall, with blue eyes and of slim build. She has a tattoo on her left arm of the name "Harley" and a tattoo of the name "Layla" on her right arm."

Roxanne also has links to the Barnard Castle area of County Durham.

Police are particularly concerned as she is on medication and has not taken it with her.

Anyone who was in The Goose pub on Wednesday around teatime and who may have seen Roxanne, or anyone who has information regarding her whereabouts is asked to contact police in Hartlepool on 01642-326326.