Sunderland striker Niall Quinn faces a late fitness test before the match against his former club Arsenal at the Stadium of Light.

But the Black Cats should be boosted by the return of defender Emerson Thome, while Jason McAteer is set for his home debut.

The Gunners still have Ashley Cole, Tony Adams, Lee Dixon, David Seaman and Francis Jeffers on the sidelines.

Ben Thatcher is set to make his first Premiership start of the season for Tottenham when they meet in-form Middlesbrough at White Hart Lane.

Everton welcome back Scot Gemmill, Paul Gascoigne, Dave Unsworth and Alan Stubbs for the visit of Newcastle.

The Magpies' veteran midfielder Rob Lee will miss the clash because of a back injury.

Table-toppers Leeds take on champions Manchester United in a potentially explosive Premiership clash this weekend.

The bitter rivals clash at 12 noon on Saturday with David O'Leary's side looking for their first win at Old Trafford since 1981.

Red Devils skipper Roy Keane could miss the match because of a knee injury.

Third placed Aston Villa will be hoping to continue their march up the table when they play host to Bolton.

Striker Juan Pablo Angel will return for Villa while keeper Steve Banks makes his Premiership debut for the Trotters.

Liverpool will be without the injured Sami Hyypia but could recall Michael Owen and Steven Gerrard for the trip to Charlton.

The Londoners have put Andy Todd on the transfer list after his training ground bust-up with keeper Dean Kiely.

Fulham hope to return to winning ways when they meet struggling Southampton at Craven Cottage.

New Saints boss Gordan Strachan is without injured duo Stuart Ripley and James Beattie.

On Sunday, Derby face a tough match at Pride Park against Chelsea.

The Blues will be keen to bounce back after losing their unbeaten Premiership record at West Ham on Wednesday.

Ipswich play host to West Ham at Portman Road, but the Tractor Boys will be missing injury victims Finidi George and Titus Bramble.

The Hammers' Czech Republic defender Tomas Repka returns after a two-match ban.