Here's a roundup of some of the main coronavirus talking points from the last 24-hours:

  • Anti-lockdown campaigners marched through London in protest at Government restrictions aimed at curbing coronavirus. Led by former Labour leader Jeremy Corbyn’s brother Piers, demonstrators chanted “stick your poison vaccine up your arse”, “take off your masks” and “we are the 99%” as they walked down Oxford Street on Saturday. Some carried placards blaming the virus on the new 5G network, while others claimed the virus itself was a hoax. The protest comes on the day London was placed in Tier 2 lockdown measures, meaning Londoners are now banned from meeting people from outside their household indoors, and a maximum of six outdoors.
  • Confusion has been cast over lockdown talks between Downing Street and Greater Manchester after mayor Andy Burnham denied No 10’s suggestion talks had been arranged to attempt to end the row. Downing Street said a call between the two sides had been scheduled for Sunday morning, as both sides come under pressure to come to an agreement over Tier 3 coronavirus restrictions. But the office for Mr Burnham, who is resisting the highest level of controls without more financial support for workers and businesses, flatly denied a call had been scheduled.
  • A two-week circuit-breaker lockdown is to be introduced in Wales from next week, according to a leaked letter. The lockdown will begin at 6pm on October 23 and last until November 9, and will see all but essential retail outlets close. The details of the plan were contained in a letter from a regional director of the Confederation of Passenger Transport to its members in Wales, which was posted on Twitter. In the letter, dated October 16, John Pockett writes: “The Welsh Government will announce on Monday a ‘circuit break’ lockdown to begin at 1800 on Friday October 23 and continue in force until 0001 on Monday, November 9.
  • A further 86 people who tested positive for coronavirus have died in hospital in England, bringing the total number of confirmed deaths reported in hospitals to 30,910, NHS England said on Saturday.Patients were aged between 44 and 99. All but two patients, aged 62 and 79, had known underlying health conditions. The deaths were between September 16 and October 16. Three other deaths were reported with no positive Covid-19 test result.
  • The Government said that, as of 9am on Friday, there had been a further 16,171 lab-confirmed cases of coronavirus in the UK. The Government also said a further 150 people had died within 28 days of testing positive for Covid-19, as of Saturday. This brings the UK total to 43,579. Separate figures published by the UK’s statistics agencies show there have now been 58,500 deaths registered in the UK where Covid-19 was mentioned on the death certificate. It brings the total number of cases in the UK to 705,428. The number of Covid-19 patients admitted to hospital on Thursday – the most recent daily figures available – and the total number of patients in hospital and those on ventilators in North East & Yorkshire as of Saturday is (previous week’s figure in brackets): 184 admitted (125), 1,165 in hospital (847), 109 on ventillators (97)