Durham were down to two fit bowlers in Chris Rushworth and debutant off-spinner Ryan Pringle, who both took some savage treatment from Trescothick in an innings of 133.
“He’s still one of the world’s best batsmen when he’s in that mood,” said Collingwood.
“Ryan will be able to talk in the future about bowling to him on his debut and say that he got him out. But it was a tough job for him.
“Marcus is a nightmare to set a field to because wherever you put the fielders he hits it somewhere else. Some of his shots were incredible.”
Two of the bowlers who started the match were off the field and a third was unfit to bowl as Somerset sped home either side of a four-hour break following a torrential downpour.
Scott Borthwick is expected to be out for at least two weeks through his second finger injury, while Jamie Harrison has a sore knee. Mark Wood was on the field but didn’t bowl because his side had stiffened up.
Graham Onions has had a second injection following the back injury he suffered at Hove 12 days ago and his chances of being fit to play against Nottinghamshire at Trent Bridge on Sunday are improving.
“Our injuries are getting a bit annoying,” said Collingwood. “It would have been good to see Scott bowling into the rough outside Marcus’s off stump. That could have been a real battle.
“Things are getting a bit desperate and we’ll have to take stock before Trent Bridge. Harrison and Wood are a worry and I don’t quite understand why they keep getting injured.
“They have had a heavy workload, which puts a lot of pressure on a young body and they are not getting through it.
“But we are not a county who make excuses. We haven’t been at our best in the first five games, but we will find a way to get there.
“We lost heavily at Edgbaston early last season then went on a good run. It’s amazing how quickly things can turn around.
“We were always chasing this game after choosing to bat then getting bowled out for 155. From that point we did an excellent job of trying to get back into it, but we were short of resources in the end.”